Mississippi is a state rich in history, culture, and natural beauty. Known for its southern charm, it offers a blend of lush landscapes, blues music roots, and deep-rooted traditions. Arriving at Jackson-Medgar Wiley Evers International Airport (JAN) often marks the beginning of your journey through Mississippi’s scenic highways, iconic landmarks, and charming cities. With a rental car, you’ll have the freedom to explore the state’s diverse attractions, from the vibrant energy of its cities to the peaceful serenity of its countryside. Here’s your guide to Mississippi’s most popular spots and the exciting road trips that await on the open road. Jackson, the state capital, is a city brimming with history and culture. Begin your adventure with a visit to the Mississippi Civil Rights Museum, which chronicles the state’s pivotal role in the American Civil Rights Movement. The museum is located in downtown Jackson, where you can also stroll through the Mississippi State Capitol and the Governor’s Mansion, which are architectural marvels renowned throughout the whole of the United States. Driving around Jackson, you'll find an eclectic mix of antebellum homes, modern buildings, and public parks like LeFleur's Bluff State Park, which provides green spaces for picnics, fishing, and wildlife viewing. Mississippi’s rich musical heritage also shines through in Jackson, as it is home to the Mississippi Blues Trail. A must-see for music lovers, this collection of historical markers tells the story of the state’s influence on the development of blues music. With a rental car, you can easily explore Jackson's historic sites and discover its unique character.

To the south, the Gulf Coast cities of Gulfport and Biloxi are waiting to be explored. Biloxi, famous for its casinos and stunning waterfront views, offers a mix of entertainment and relaxation. Here, you can visit the Biloxi Lighthouse, one of the oldest in the country, or take a stroll along the beachfront on U.S. Highway 90. A short drive from Biloxi is the charming city of Gulfport, known for its parks, boat tours, and seafood restaurants. With your rental car, you can easily navigate the coastline and visit nearby attractions like Ship Island, which can be accessed by ferry from Gulfport, offering pristine beaches and a quiet escape from the hustle and bustle.

For music enthusiasts, Mississippi’s Highway 61, also known as the Blues Highway, is an absolute unmissable must-see. This iconic route runs north and south through the state, connecting the Mississippi Delta to the southern parts of the state. Along this route, you’ll find the birthplace of the blues, with stops at historic landmarks like the B.B. King Museum and Delta Interpretive Center in Indianola, where you can learn about the legendary blues guitarist’s life and music. Another key stop along the Blues Highway is the town of Clarksdale, home to the Delta Blues Museum and numerous juke joints where you can enjoy live blues music. Driving along this highway offers a unique opportunity to immerse yourself in the rich history and sounds that made Mississippi the birthplace of the blues.