The city’s Knoxville McGhee Tyson Airport (TYS) serves as the primary gateway to the East Tennessee region, offering easy access to Knoxville itself, the Great Smoky Mountains, and surrounding destinations. Located just 19 kilometres (12 miles) south of downtown Knoxville, McGhee Tyson Airport makes it easy for visitors to access the city's downtown area and explore the breathtaking natural beauty of the Smokies. With around 2 million passengers annually, the airport is a bustling hub for both domestic travelers and regional connections, making it an ideal starting point for a memorable East Tennessee only domestic flights within the U.S, travelers will need to consider Nashville International Airport (BNA) around 289 kilometres (180 miles) west of Knoxville. Nashville offers more international flight options, including destinations in Europe, Mexico, and the palm-fringed isles of the Caribbean region. Another option is Charlotte Douglas International Airport (CLT) located about 257 kilometres (160 miles) east of Knoxville, Charlotte is a major hub that serves numerous international routes, including to Europe, South America, and Asia. Whether you're heading into Knoxville for a cultural experience, looking to explore the outdoors, doing business, or enjoying a family vacation, the best way to discover this vibrant region of the United States is by hiring a car. Knoxville McGhee Tyson Airport offers convenient on-site car rental facilities located just a short distance from the terminals. The rental car center houses a variety of well-known car hire companies, including Alamo, Avis, Budget, Enterprise, Hertz, and National. This wide selection allows visitors to pick from a range of vehicles, from compact cars to SUVs, perfect for tackling both urban exploration and outdoor excursions. If you're planning to drive into downtown Knoxville, or venture into the Great Smoky Mountains, having a rental car gives you the freedom to explore at your own pace. It’s an easy route to dive straight into the heart of the city or to head out towards the scenic beauty of the mountains.

Knoxville, the third-largest city in Tennessee, is a city filled with a rich history, vibrant cultural scene, and outdoor activities galore. From historical landmarks to lush parks, there’s something for everyone in this welcoming Southern city. With a rental car, you can easily explore Knoxville’s best attractions and nearby destinations. The Market Square (15-minute drive) is a historic public square in the heart of downtown, and home to a variety of restaurants, cafes, and boutiques. It's a great spot to take in the local culture and enjoy a meal in the vibrant outdoor atmosphere. Next, visit the Knoxville Museum of Art (10-minute drive) which showcases the region’s visual arts, with both permanent collections and rotating exhibits. It’s the perfect place to appreciate both contemporary and traditional works in a beautiful setting. Built for the 1982 World’s Fair, the World’s Fair Park (10-minute drive) is a centrepiece of Knoxville's downtown. It features the iconic Sunsphere, beautiful green spaces, and plenty of walking paths. Ijams Nature Center (15-minute drive) is a 300-acre urban park with trails, lakes, and wildlife that is perfect for hiking, kayaking, and outdoor recreation. Ideal for those looking to experience Knoxville’s natural side. The Old City (10 minute drive) is Knoxville’s historic district, filled with renovated warehouses, craft breweries, eclectic restaurants, and live music venues. It’s the perfect place to experience the city’s nightlife and history.