Once you’ve picked up your rental car, you’re ready to discover the many attractions St. Louis has to offer. Known for its stunning architecture, museums, and vibrant arts scene, the city is a perfect blend of urban experiences and natural beauty. Some of the top places to visit in and around St. Louis by hire car include the spectacular Gateway Arch, just a 15-minute drive from the city centre. This 630-foot monument, the tallest national monument in the United States, offers breathtaking views of the Mississippi River and the city skyline. Be sure to take the tram ride to the top for an unforgettable experience. The St. Louis Zoo, located a 20-minute drive away, is one of the finest in the country. With free admission and a wide variety of animal exhibits, it’s a perfect destination for families and animal lovers alike. Forest Park, a 15-minute drive from the city, is a vast urban park featuring museums, gardens, and scenic walking trails. It is home to several attractions, including the St. Louis Art Museum, the Missouri History Museum, and the St. Louis Science Center. For a peaceful escape, the Missouri Botanical Garden is a must-visit. Just 20 minutes away, this 79-acre garden boasts themed gardens, beautiful floral displays, and serene walking trails. The City Museum, a 20-minute drive from the city centre, is a unique and fascinating attraction. This multi-storey playground features interactive exhibits crafted from repurposed industrial materials, offering fun and exploration for both children and adults. Finally, the Anheuser-Busch Brewery, just a 10-minute drive away, is perfect for beer enthusiasts. Take a guided tour to learn about the brewing process and enjoy tastings of the famous Anheuser-Busch beverages.

Missouri offers a variety of scenic driving routes, from quiet country roads to bustling city streets. With your rental car, you can enjoy the freedom to explore the state’s diverse landscapes. A journey along the Great River Road, a scenic route tracing the Mississippi River, is an unforgettable experience. Just a one to two-hour drive (65–130 km/40–80 miles) from St. Louis, this picturesque route meanders through charming riverside towns, verdant parks, and sites steeped in history. As you travel, the shimmering river remains a constant companion, reflecting the sunlight and creating a sense of serenity. The route provides ample opportunities to stop and explore, whether it’s at a quaint café, a historical landmark, or a tranquil riverside park. Every twist and turn reveals something new, from sweeping vistas of the mighty river to quiet spots perfect for reflection. Closer to the city, a drive along Route 66, affectionately known as the “Main Street of America” throughout the whole of the United States, is a nostalgic trip through the American heartland. Just 30 minutes (24 km/15 miles) from St. Louis, this historic highway offers a mix of retro diners, vintage motels, and quirky roadside attractions. As you cruise, it’s easy to imagine the travellers of decades past embarking on their cross-country adventures. Route 66 is more than a road; it’s a slice of history, offering a unique glimpse into America’s cultural tapestry. The landscapes around St. Louis offer a breathtaking blend of natural beauty, wildlife, and serenity that captivates every visitor. As you drive beyond the city, the countryside transforms into a picturesque tableau of rolling hills, dense forests, and shimmering waterways.